History
June 2020
CE Certificate
for
MSM® DEPERI - peripheral Drug Eluting Balloon
July 2019
Market
introduction of MSM® CARDIO - Wireless Pocket Ultrasound
System
2019
EC Certificate for a
new coronary product
2017
EC Certificates of
new peripheral products
2016
EC Certificates of
new coronary products
2015
Development of new
coronary products
2014
Development of new
peripheral products
December 2010
EC
Certification for Galaxy PTCA dilatation catheter,
Galaxy
HP High Pressure PTCA Balloon Catheter,
Uni-Pass
Hemostasis valve,
Marathon coronary stent system,
Comet
coronary stent system
Certificate Number: 974 B CE for use the CE 0473
marking.
August 2010
EC
Certification for Nova, SuperNova, Stream
Certificate Number: 974 CE for use the CE 0473
marking.
July 2010
introduction of
quality management system according to DIN EN ISO
13485:2010
January 2010
R/D of
Aspiration catheter "Stream"
November 2009
R/D of PTA
balloon catheter "SuperNova 0.014" for "Below the Knee"
indication
December 2008
R/D of PTA
balloon catheter "Nova 0.035"
July 2007
introduction of
quality management system according to DIN EN ISO 13485:2003
October 2006
R/D of plasma
- implanted nano-technologie surfaces for heart implants -
e.g. Plug, Occluder, ...
September 2005
R/D of
nano-technology surfaces for medical implants - e.g. Vena Cava
Filter
December 2004
MSM® presents a new DES (Drug Eluting
Stent) Generation with
"Intima-like" Coating Technology: Known proven
Paclitaxel w/w approved drug with a dose of 1
µg/mm² ± 5%.
Release of about 10% during Early Burst Rate within the first
2 days; Release of about 30% during Therapeutic Period within
4 weeks; about 40% release after 6 month.
November 2004
market
introduction of MSM®
LASER COBALT CHROMIUM - Stent with surface
nano-technology. MSM® Coronary Stent has rounded thin
struts for easy access - down to .0028" strut
thickness.Best clinical outcomes by extraordinary high
bio-compatibility! ( ISAR STEREO II-trial: Schühlen, H.
et al.; presented at TCT 2002; "Less restenosis because
of thinner struts").
October 2004
market introduction of MSM® -
LASER TANTALUM CHROMIUM - Stent with surface
nano-technology! This MSM® Coronary Stent is made like a
tantalum chromium superalloy on
"sandwich"-
technology that allows us to reduce strut
thickness without compromising radio-opacity and radial
strength. Best clinical outcomes by extraordinary high
biological compatibility! Just .0024" thick ! ( ISAR
STEREO II-trial: Schühlen, H. et al.; presented at TCT
2002; "Less restenosis because of thinner struts").
September 2004
R/D of a
new Stent Delivery System CIS (Coronary
Implant System): Atraumatic rounded micro soft tip at the top
of a tapered minimized lesion entry profile .017".
Tailor-made balloon shoulders with 30° cone angles.
Optimized balloon length with max. 0.5 mm overhang. Minimum
system profile .376". Hydrophilic coated - Semi
compliant. Optimized transition zone with tapered hypotube for
kink protection and continuous stiffness decrease from
proximal to distal shaft.
August 2004
MSM® is
recognized as leader in stent innovation and multiple stent
coatings with surface nano-technology.
March 2003
market-introduction of a "POL-surface"
(ProtectiveOxideLayer)
January 2003
market-introduction of "bio-ceram" product
line
Dezember 2002
US-patent
issue, STENT FOR TRANSLUMINAL IMPLANTATION, Patent No. US
6.497.723
September 2002
Appl. No.
09/486.794 for MSM-Stent; result of long term trial with
high-risk patients show outstanding low re-stenosis of 15%
June 2002
value line -
euco-Stent and euco-CIS-System
March 2002
market-introduction of MSM dental product line
December 2001
MSM AG is
manufacturing approx. 75 different products
October 2001
market-introduction of BMS-Stent length 21 mm
March 2001
market-introduction of stent lengths 6 mm and 12 mm as
small vessel (vs) BMS-Stents, also to apply as
Primary-CIS-System
February 2000
market-introduction of a value stent product line
"HT"
December 1999
MSM AG is
manufacturing approx. 50 different products
June 1999
market-introduction of a small vessel (sv) version, to
be used for primary-stenting-procedures (Direct Stenting) -
too
May 1999
introduction of
quality management system according to
ISO 9001 and EN 46001
December 1998
MSM AG is
manufacturing approx. 35 different products, like
coronary-Bare-Stents, CIS-Systems and PTCA-Catheters
October 1998
begin of
research regarding Bioresorbable Vascular Stents
June 1998
introduction of
quality management system according to
ISO 9002 and EN 46002
April 1998
market-introduction of a Coronar Implant System (CIS),
a PTCA-Catheter with a premounted MSM-Stent (BMS or HV)
March 1998
market-introduction of PTCA-Catheter
October 1997
market-introduction of high vaccum treated
"Bare"-Stents (HV)
September 1997
begin of
long term trial (5 years) with high-risk patients, University
Hospital of Ulm - cardiological department
August 1997
market-introduction of "Bare"-Stents with a
Bio-Metal-Surface "BMS" after receiving CE-approval
April 1997
foundation of
"Micro Science Medical AG" (MSM AG), a developing
and manufacturing company
August 1996
beginning of coronary Stent development by Euco Medical GmbH
and engineering-office Bernd Starck